Why not? Every time my husband talks to his mother on the phone, she asks if I have used any of the fabric she has given me, so now, yes, I have. I made some "Flower Shop" blocks to practice edge stitching the applique, and I used some fabric she sent me as the background. Unfortunately, I didn't have much of the good fusible from MO left, so I used some stuff I already had. Hate it. Don't even really know what it is (suspect woven fusible from the t-shirt quilt), but it drives home the point you need to know the properties of the materials you are using.